Adenosine receptors and asthma

P138: Are Depression and Anxiety Affected by Adenosine A2A Receptors?

Adenosine acts as neuromodulator in the brain, which its involvement in a wide range of brain processes and diseases has been studied, such as epilepsy, sleep, anxiety, panic disorder, Alzheimer’s disease, Parkinson’s disease and schizophrenia. Adenosine receptors have been detected: A1R, A2AR (A2AR), A2BR, and A3R. A1R and A2R inhibit cAMP production, while A2AR and A2BR stimulate cAMP product...

Adenosine and adenosine receptors in rheumatoid arthritis

Rheumatoid arthritis is one of the most important chronic, progressive and disabling inflammatory diseases characterized by joint destructive process associated with synovial proliferation and secretion of high levels of proinflammatory mediators including cytokines and growth factors. Early diagnosis and effective therapy are crucial in order to prevent unfavorable outcome with joint deteriora...

Adenosine receptors and angiogenesis.

Copyright © 2007 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online TX 72514 Circulation Research is published by the American Heart Association. 7272 Greenville Avenue, Dallas, DOI: 10.1161/CIRCRESAHA.107.165761 2007;101;1075-1077 Circ. Res. John A. Auchampach Adenosine Receptors and Angiogenesis http://circres.ahajournals.org/cgi/content/full/101/11/1075 located on...

Adenosine receptors and cancer.

The A(1), A(2A), A(2B) and A(3) G-protein-coupled cell surface adenosine receptors (ARs) are found to be upregulated in various tumor cells. Activation of the receptors by specific ligands, agonists or antagonists, modulates tumor growth via a range of signaling pathways. The A(1)AR was found to play a role in preventing the development of glioblastomas. This antitumor effect of the A(1)AR is m...

Adenosine receptors and its ligands